AbbVie Inc. discovers, develops, manufactures, and sells pharmaceuticals in the worldwide. The company offers HUMIRA, a therapy administered as an injection for autoimmune and intestinal Behçet's diseases; SKYRIZI to treat moderate to severe plaque psoriasis in adults; RINVOQ, a JAK inhibitor for the treatment of moderate to severe active rheumatoid arthritis in adult patients; IMBRUVICA to treat adult patients with chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and VENCLEXTA, a BCL-2 inhibitor used to treat adults with CLL or SLL; and MAVYRET to treat patients with chronic HCV genotype 1-6 infection. It also provides CREON, a pancreatic enzyme therapy for exocrine pancreatic insufficiency; Synthroid used in the treatment of hypothyroidism; Linzess/Constella to treat irritable bowel syndrome with constipation and chronic idiopathic constipation; Lupron for the palliative treatment of advanced prostate cancer, endometriosis and central precocious puberty, and patients with anemia caused by uterine fibroids; and Botox therapeutic. In addition, the company offers ORILISSA, a nonpeptide small molecule gonadotropin-releasing hormone antagonist for women with moderate to severe endometriosis pain; Duopa and Duodopa, a levodopa-carbidopa intestinal gel to treat Parkinson's disease; Lumigan/Ganfort, a bimatoprost ophthalmic solution for the reduction of elevated intraocular pressure (IOP) in patients with open angle glaucoma (OAG) or ocular hypertension; Ubrelvy to treat migraine with or without aura in adults; Alphagan/ Combigan, an alpha-adrenergic receptor agonist for the reduction of IOP in patients with OAG; and Restasis, a calcineurin inhibitor immunosuppressant to increase tear production, as well as other eye care products. AbbVie Inc. has a research collaboration with Dragonfly Therapeutics, Inc. The company was incorporated in 2012 and is headquartered in North Chicago, Illinois.

AbbVie Inc.

Statement of Changes in Beneficial Ownership

Initial Statement of Beneficial Ownership

Insider	Title	Date	Shares	% Owned	Market Value
Richard A. Gonzalez	Executive Chairman Show All	2024-08-05	446.6K	0.02528%	$82.33M
Laura J. Schumacher	Director, Independent Lead Director, Independent Director Show All	2023-01-31	248K	0.01404%	$45.72M
Azita Saleki-Gerhardt	Executive VP & COO, Independent Director Show All	2024-02-28	226.17K	0.0128%	$41.7M
Thomas Craig Freyman	Independent Director, Director Show All	2024-05-03	125.22K	0.00709%	$23.09M
Thomas J. Hudson	Vice Chairman, Member of the Scientific Advisory Board, Director Show All	2024-02-28	107.27K	0.00607%	$19.78M
Robert A. Michael
Jeffrey Ryan Stewart
Nicholas J. Donoghoe
Elaine K. Sorg
Brian L. Durkin
Glenn F. Tilton
Carrie C. Strom
Roopal Thakkar
Edward Joseph Rapp
Scott T. Reents